ATP Synthase subunit alpha

E6762Hu

Sandwich

48T,96T

3.67ng/L

7-1500ng/L

Serum, plasma, cell culture supernates

Human

2-8ºC

1h 30m

ATP synthase F1 subunit alpha, mitochondrial is an enzyme that in humans is encoded by the ATP5F1A gene. This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the same protein have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16.

59,751

498

ATP Synthase F1 subunit alpha;ATP Synthase subunit alpha, mitochondrial;ATP5A;ATP5A1;ATP5AL2;ATPM;COXPD22;hATP1;HEL-S-123m;MC5DN4;MOM2;OMR;ORM;

ATP5F1A

Tags & Cell Markers; Signal Transduction; Metabolism

ATP5A1