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Home > Product > ELISA Kit > Human Epithelial Discoidin Domain-containing Receptor 1, DDR1 ELISA Kit

Human Epithelial Discoidin Domain-containing Receptor 1, DDR1 ELISA Kit

Human Epithelial Discoidin Domain-containing Receptor 1, DDR1 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.028ng/ml

Detection range: 0.05-20ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 0.028ng/ml

Detection range: 0.05-20ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Epithelial Discoidin Domain-Containing Receptor 1

Code

E5258Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.028ng/ml

Detection range

0.05-20ng/ml

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the Matrix Metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.

UniProt accession

MASS(Da)

101,128

GeneID

780

Synonyms

CD antigen CD167a;CD167 antigen-like family member A;Cell adhesion kinase;DDR 1;DDR1;Discoidin receptor tyrosine kinase;Epithelial discoidin domain receptor 1;Epithelial discoidin domain-containing receptor 1;HGK2;Mammary carcinoma kinase 10;MCK-10;Protein-tyrosine kinase 3A;Protein-tyrosine kinase RTK-6;TRK E;Tyrosine kinase DDR;Tyrosine-protein kinase CAK

Gene names

DDR1

Research area

Others

Target protein

DDR1

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of Human Epithelial Discoidin Domain-containing Receptor 1, DDR1 ELISA Kit are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
12ng/ml 1.867 1.98 1.93
2.093
6ng/ml 0.94 0.937 0.887
0.935
3ng/ml 0.393 0.496 0.446
0.599
1.5ng/ml 0.307 0.272 0.222
0.236
0.75ng/ml 0.153 0.137 0.087
0.122
0ng/ml 0.035 0.05 0
0.065

Precision

We measured random samples of E5258Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 9.7 0.23 2.4
Intra-Assay 2 18 5.2 0.24 4.6
Intra-Assay 3 18 3.1 0.14 4.7

Protocols

References

Customer reviews and Q&As

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Product size

Price

  • 48T

    $320.00

  • 96T

    $458.00

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Lead time: Within one week

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