Long-Chain Fatty Acid Transport Protein 4

E5594Hu

Sandwich

48T,96T

23.42ng/L

50-10000ng/L

Serum, plasma, cell culture supernates

Human

2-8ºC

1h 30m

Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane (PubMed: 12556534, PubMed: 21395585). Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs) (PubMed: 24269233). Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis (By similarity). Probably involved in fatty acid transport across the blood barrier (PubMed: 21395585). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones (By similarity).

72,064

10999

ACSVL4;Arachidonate--CoA ligase;FATP-4;Fatty acid transport protein 4;Long-chain fatty acid transport protein 4;Long-chain-fatty-acid--CoA ligase;SLC27A4;Solute carrier family 27 member 4;Very long-chain acyl-CoA synthetase 4;

SLC27A4

Neuroscience

SLC27A4