Glutamate Oxaloacetate Transaminase 1

E1141Ra

Sandwich

48T,96T

1.07U/L

2-600U/L

Serum, plasma, cell culture supernates

Rat

2-8ºC

1h 30m

Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

46,429

24401

Aspartate aminotransferase, cytoplasmic;cAspAT;cCAT;Cysteine aminotransferase, cytoplasmic;Cysteine transaminase, cytoplasmic;Glutamate oxaloacetate transaminase 1;GOT 1;GOT1;Transaminase A;

GOT1

Signal Transduction

GOT1