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Home > Product > ELISA Kit > Rat Cop9 Signalosome Compex Subunit 1, GPS1 ELISA Kit

Rat Cop9 Signalosome Compex Subunit 1, GPS1 ELISA Kit

Rat Cop9 Signalosome Compex Subunit 1, GPS1 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.03ng/ml

Detection range: 0.05-30ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Rat

Product Summary

Size: 48T,96T

Sensitivity: 0.03ng/ml

Detection range: 0.05-30ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Rat

Product overview

Full product name

Cop9 Signalosome Compex Subunit 1

Code

E1192Ra

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.03ng/ml

Detection range

0.05-30ng/ml

Sample type

Serum, plasma, cell culture supernates

Species

Rat

Storage

2-8ºC

Assay time

1h 30m

Background

Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction (By similarity).

UniProt accession

MASS(Da)

53,428

GeneID

117039

Synonyms

COP9 signalosome complex subunit 1;G protein pathway suppressor 1;GPS 1;GPS1;GPS-1;JAB1-containing signalosome subunit 1;MFH protein;SGN1;Signalosome subunit 1;

Gene names

GPS1

Research area

Others

Target protein

GPS1

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E1192Ra are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
20ng/ml 2.257 2.234 2.188
2.212
10ng/ml 1.95 1.949 1.902
1.947
5ng/ml 1.253 1.27 1.223
1.287
2.5ng/ml 0.722 0.669 0.623
0.617
1.25ng/ml 0.444 0.425 0.379
0.407
0ng/ml 0.04 0.047 0
0.054

Precision

We measured random samples of E1192Ra within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 2.9 0.15 5.3
Intra-Assay 2 18 7.6 0.43 5.7
Intra-Assay 3 18 1.7 0.07 4.4

Protocols

References

Customer reviews and Q&As

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  • Size

    Code

    Price

  • 48T

    E1192Ra

    $320.00

  • 96T

    E1192Ra

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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