Full product name
Gap junction beta-2 protein
Code
BT-AP07988
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthetic Peptide of Connexin-26
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness.
Uniprot accession
Gene ID
Human: 2706
Synonyms
Gap junction beta-2 protein ;Connexin-26;Cx26; GJB2; Gap junction beta-2 protein; Connexin-26; Cx26
Research area
Neuroscience; Signal transduction
Target protein
GJB2