Full product name
Telomeric repeat-binding factor 2
Code
BT-AP14863
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 130-210
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
Uniprot accession
Gene ID
Human: 7014
Synonyms
Telomeric repeat-binding factor 2 ;TTAGGG repeat-binding factor 2;Telomeric DNA-binding protein
Research area
Epigenetics and nuclear signaling; Cancer
Target protein
TERF2